Professor Stephen Brett Consultant in intensive care medicine

Background

Professor Stephen Brett completed his undergraduate education at the University of Birmingham, and has served with the regular army. He undertook his specialist training in London and is a Doverdale fellow in critical care at the Royal Brompton Hospital. He completed his MD thesis in pulmonary vascular control.

Professor Brett has been a consultant in intensive care medicine at Hammersmith Hospital since 1998. He is currently president of the Intensive Care Society. As well as taking on the role of reader in critical care at Imperial College, London, he also sits on many external advisory boards, trial steering groups and data & safety committees.

Expertise

General critical illness, Multiple organ failure, Severe acute pancreatitis, Recovery after myocardial infarction and cardiac arrest, Prolonged recovery after cardiothoracic surgery, Post surgical care, Sepsis and severe infection

Research & publications

Critical care with research interests ranging from clinical trials to epidemiology and human factors.

Recent publications:

Corner EJ, Hichens LV, Attrill KM, Vizcaychipi MP, Brett SJ, Handy JMet al., 2015, The responsiveness of the Chelsea Critical Care Physical Assessment tool in measuring functional recovery in the burns critical care population: An observational study,BURNS, Vol: 41, Pages: 241-247, ISSN: 0305-4179

D'Lima DM, Moore J, Bottle A, Brett SJ, Arnold GM, Benn Jet al., 2015, Developing effective feedback on quality of anaesthetic care: what are its most valuable characteristics from a clinical perspective?, JOURNAL OF HEALTH SERVICES RESEARCH & POLICY, Vol: 20, Pages: 26-34, ISSN: 1355-8196

Hernandez-Silveira M, Ahmed K, Ang SS, Zandari F, Mehta T, Weir R, Burdett A, Toumazou C, Brett SJet al., 2015, Assessment of the feasibility of an ultra-low power, wireless digital patch for the continuous ambulatory monitoring of vital signs., BMJ Open, Vol: 5, Pages: e006606-e006606,

Hill NE, Fallowfield JL, Delves SK, Ardley C, Stacey M, Ghatei M, Bloom SR, Frost G, Brett SJ, Wilson DR, Murphy KGet al., 2015, Changes in Gut Hormones and Leptin in Military Personnel During Operational Deployment in Afghanistan, OBESITY, Vol: 23, Pages: 608-614, ISSN: 1930-7381

Hill NE, Saeed S, Phadke R, Ellis MJ, Chambers D, Wilson DR, Castells J, Morel J, Freysennet DG, Brett SI, Murphy KG, Singer Met al., 2015, Detailed Characterization of a Long-Term Rodent Model of Critical Illness and Recovery, CRITICAL CARE MEDICINE, Vol: 43, Pages: E84-E96, ISSN: 0090-3493

Hill NE, Woods DR, Delves SK, Murphy KG, Davison AS, Brett SJ, Quinton R, Turner S, Stacey M, Allsopp AJ, Fallowfield JLet al., 2015, The gonadotrophic response of Royal Marines during an operational deployment in Afghanistan, ANDROLOGY, Vol: 3, Pages: 293-297, ISSN: 2047-2919

Moore AC, Stacey MJ, Bailey KG, Bunn RJ, Woods DR, Haworth KJ, Brett SJ, Folkes SEet al., 2015, Risk factors for heat illness among British soldiers in the hot Collective Training Environment., Journal of the Royal Army Medical Corps, Pages: 1-6, ISSN: 0035-8665

Nyland GA, Mckenzie BC, Myles PR, Semple MG, Lim WS, Openshaw PJM, Read RC, Taylor BL, Brett SJ, Mcmenamin J, Enstone JE, Bannister B, Nicholson KG, Nguyen-van-Tam JSet al., 2015, Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK, EPIDEMIOLOGY AND INFECTION, Vol: 143, Pages: 1129-1138, ISSN: 0950-2688

Petrie J, Easton S, Naik V, Lockie C, Brett SJ, Stuempfle Ret al., 2015, Hospital costs of out-of-hospital cardiac arrest patients treated in intensive care; a single centre evaluation using the national tariff-based system, BMJ OPEN, Vol: 5, ISSN: 2044-6055

Stacey MJ, Brett S, Woods D, Jackson S, Ross Det al., 2015, Case ascertainment of heat illness in the British Army: evidence of under-reporting from analysis of Medical and Command notifications, 2009-2013., J R Army Med Corps, ISSN: 0035-8665

Stacey MJ, Parsons I, Woods DR, Taylor PN, Ross D, Brett SJet al., 2015, Susceptibility to exertional heat illness and hospitalisation risk in United Kingdom military personnel, BMJ Open Sports and Exercise Medicine, Vol: 1, ISSN: 2055-7647

Wandrag L, Brett SJ, Frost G, Hickson Met al., 2015, Impact of supplementation with amino acids or their metabolites on muscle wasting in patients with critical illness or other muscle wasting illness: a systematic review, JOURNAL OF HUMAN NUTRITION AND DIETETICS, Vol: 28, Pages: 313-330, ISSN: 0952-3871

Brett S, Hatch R, 2014, Characterising early recovery in survivors of cardiac arrest, RESUSCITATION, Vol: 85, Pages: 454-455, ISSN: 0300-9572

Corner EJ, Brett SJ, 2014, Early identification of patients at risk of long-term critical illness-associated physical disability: is it possible?, Critical Care, Vol: 18, ISSN: 1466-609X

Corner EJ, Soni N, Handy JM, Brett SJet al., 2014, Construct validity of the Chelsea critical care physical assessment tool: an observational study of recovery from critical illness, CRITICAL CARE, Vol: 18, ISSN: 1466-609X

Fallowfield JL, Delves SK, Hill NE, Cobley R, Brown P, Lanham-New SA, Frost G, Brett SJ, Murphy KG, Montain SJ, Nicholson C, Stacey M, Ardley C, Shaw A, Bentley C, Wilson DR, Allsopp AJet al., 2014, Energy expenditure, nutritional status, body composition and physical fitness of Royal Marines during a 6-month operational deployment in Afghanistan, BRITISH JOURNAL OF NUTRITION, Vol: 112, Pages: 821-829, ISSN: 0007-1145

Gordon AC, Mason AJ, Perkins GD, Ashby D, Brett SJet al., 2014, Protocol for a randomised controlled trial of VAsopressin versus Noradrenaline as Initial therapy in Septic sHock (VANISH), BMJ OPEN, Vol: 4, ISSN: 2044-6055

Gordon AC, Mason AJ, Perkins GD, Stotz M, Terblanche M, Ashby D, Brett SJet al., 2014, The Interaction of Vasopressin and Corticosteroids in Septic Shock: A Pilot Randomized Controlled Trial, CRITICAL CARE MEDICINE, Vol: 42, Pages: 1325-1333, ISSN: 0090-3493

Parnia S, Yang J, Inigo-Santiago L, Ahn A, Zhu J, Nasir A, Golder K, Nguyen R, Ravishankar S, Bartlett P, Pogson D, Cooke S, Walker C, Spearpoint K, Brett S, Kitson D, Melody T, Chilwan M, Warlow C, Bullock S, Schoenfeld E, Nolan J, Perkins G, Deakin CDet al., 2014, Cerebral Oximetry is a Predictor of Return of Spontaneous Circulation in Cardiac Arrest, Scientific Sessions of the American-Heart-Association and American-Stroke-Association / Resuscitation Science Symposium, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 2124-2124, ISSN: 0009-7322

Patel A, Brett SJ, 2014, Identifying Future Risk From Routine Tests?*, CRITICAL CARE MEDICINE, Vol: 42, Pages: 999-1000, ISSN: 0090-3493

Patel A, Laffan MA, Waheed U, Brett SJet al., 2014, Randomised trials of human albumin for adults with sepsis: systematic review and meta-analysis with trial sequential analysis of all-cause mortality, BMJ-BRITISH MEDICAL JOURNAL, Vol: 349, ISSN: 1756-1833

Patel A, Stasiowska M, Waheed U, Brett SJ, Patel PBet al., 2014, Poor Analgesic Efficacy of Epidural Analgesia in Critical Care Patients After Pancreaticoduodenectomy, PANCREAS, Vol: 43, Pages: 373-379, ISSN: 0885-3177

Patel A, Waheed U, Brett SJ, Rahemtulla A, Apperley JF, Patel PBet al., 2014, Rapid initial response of myeloma hyperammonemic encephalopathy to L-ornithine-L-aspartate and dexamethasone therapy, LEUKEMIA & LYMPHOMA, Vol: 55, Pages: 198-200, ISSN: 1042-8194

Ramsay P, Salisbury LG, Merriweather JL, Huby G, Rattray JE, Hull AM, Brett SJ, Mackenzie SJ, Murray GD, Forbes JF, Walsh TSet al., 2014, A rehabilitation intervention to promote physical recovery following intensive care: a detailed description of construct development, rationale and content together with proposed taxonomy to capture processes in a randomised controlled trial, TRIALS, Vol: 15, ISSN: 1745-6215

Griffiths J, Hatch RA, Bishop J, Morgan K, Jenkinson C, Cuthbertson BH, Brett SJet al., 2013, An exploration of social and economic outcome and associated health-related quality of life after critical illness in general intensive care unit survivors: a 12-month follow-up study, CRITICAL CARE, Vol: 17, ISSN: 1466-609X

Myles P, Nguyen-Van-Tam JS, Semple MG, Brett SJ, Bannister B, Read RC, Taylor BL, McMenamin J, Enstone JE, Nicholson KG, Openshaw PJ, Lim WSet al., 2013, Differences between asthmatics and nonasthmatics hospitalised with influenza A infection, EUROPEAN RESPIRATORY JOURNAL, Vol: 41, Pages: 824-831, ISSN: 0903-1936

Parnia S, Santiago LI, Ahn A, Deakin C, Golder K, Bartlett P, Pogson D, Cooke S, Walker C, Spearpoint K, Brett S, Kitson D, Perkins G, Melody T, Chilwan M, Nolan J, Yang J, Zhu Jet al., 2013, The Utility of Cerebral Oximetry (rSO2%) During In-Hospital Cardiac Arrest as a Marker for the Prediction of Return of Spontaneous Circulation (ROSC), Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, ISSN: 0009-7322

Patel A, Brett SJ, 2013, Is 6% tetrastarch 130 kDa (hydroxyethyl starch 130/0.4 or 130/0.42) suitable for severe sepsis?, BRITISH JOURNAL OF HOSPITAL MEDICINE, Vol: 74, Pages: 178-178, ISSN: 1750-8460

Patel A, Brett SJ, 2013, Gelatin solutions for critically unwell septic adults., Br J Hosp Med (Lond), Vol: 74, ISSN: 1750-8460

Patel A, Laffan MA, Dazzi F, Apperley JF, Brett SJet al., 2013, Mesenchymal stromal stem cell therapy for septic shock, UK Critical Care Research Forum

Private practice

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